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  • Title: [A case of Sweet's syndrome with a variety of chest radiological findings].
    Author: Kushima H, Mizunoe S, Ishii H, Hashinaga K, Yamasaki T, Kishi K, Tokimatsu I, Hiramatsu K, Kadota J.
    Journal: Nihon Kokyuki Gakkai Zasshi; 2007 Sep; 45(9):685-90. PubMed ID: 17929470.
    Abstract:
    We report a rare case of Sweet's syndrome (acute febrile neutrophilic dermatosis) with a variety of chest radiological findings. A 73-year-old man, who had been treated with corticosteroid for Sweet's syndrome for 2 years, was admitted to our hospital because of pyrexia with a infiltrative chest shadow. Chest CT scans showed consolidation and ground-glass opacities with air-bronchogram in the right lower lobe. Treatment with antibiotics seemed to be effective but there was no improvement of chest shadows. Simultaneously with his pyrexia, diffuse centrilobular-micronodular shadows and a mass-like shadow appeared on chest CT after 2 months and after the next 2 months, respectively. Bronchoalveolar lavage fluid contained increased neutrophils but not any infectious pathogen. Transbronchial lung biopsy specimens revealed chronic interstitial infiltrate with alveolar wall thickening and neutrophil accumulation in the airspace. A diagnosis of pulmonary involvement in a patient with Sweet's syndrome was finally made and he was successfully treated with corticosteroid.
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