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  • Title: Synthesis and in vitro antibacterial properties of 2-(3-bromo-5-isoxazolylideneamino-oxy)acetamido-beta-lactam derivatives.
    Author: Sala A, Chiarino D, Napoletano M, Albini E, Carenzi A.
    Journal: Farmaco; 1991; 46(7-8):887-97. PubMed ID: 1793473.
    Abstract:
    The synthesis of new 2-(3-bromo-5-isoxazolylideneamino-oxy)acetic acids and their condensation derivatives with suitable beta-lactam nuclei is reported. Their antibacterial properties have been tested in vitro. An interesting activity against Gram-positive bacteria including beta-lactamase-producing microorganisms was found among the cephalosporanic acid derivatives.
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