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  • Title: Cytokine production by mast cells and basophils.
    Author: Galli SJ, Gordon JR, Wershil BK.
    Journal: Curr Opin Immunol; 1991 Dec; 3(6):865-72. PubMed ID: 1793528.
    Abstract:
    Mast cells and/or basophils have been implicated in the expression of a wide variety of biological responses, including immediate hypersensitivity reactions, host responses to parasites and neoplasms, angiogenesis, tissue remodeling, and immunologically non-specific inflammatory and fibrotic conditions. Recent findings suggest that an important mechanism by which mast cells influence such biological responses is through the production of a broad panel of multifunctional cytokines. In contrast, the extent to which basophils can produce cytokines is uncertain.
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