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  • Title: Acute 'upside-down' visual inversion due to multiple sclerosis.
    Author: Okuyucu EE, Okuyucu S, Karazincir S, Akoglu E, Duman T.
    Journal: Mult Scler; 2008 Mar; 14(2):266-7. PubMed ID: 17942518.
    Abstract:
    In a 20-year-old male patient, a 180 degree inversion of visual image was found as a manifestation of multiple sclerosis. Upside down reversal of vision is not a well-known sign in multiple sclerosis. Exact mechanism is still unknown. Lesions involving cortical areas, mainly the parieto-occipital region, have occasionally been documented. To our knowledge this is the first report of upside-down reversal of vision in multiple sclerosis with cerebra lesion on MRI.
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