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  • Title: Retinol deficient diet decreases binding activity of testicular fatty acid-binding protein.
    Author: Riaz-ul-Haq, Haq Z.
    Journal: Int J Vitam Nutr Res; 1991; 61(3):193-8. PubMed ID: 1794946.
    Abstract:
    Fatty acid-binding protein (FABP) activity was determined in livers and testes of retinol sufficient, retinol deficient, and also in a group of retinol deficient rats, which were refed 100 micrograms of retinyl acetate for four hours. [14C]palmitoyl CoA binding assay was used to estimate the binding activity of FABP. In retinol sufficient and retinol deficient groups, liver FABP bound 431 and 446 pmol [14C]palmitoyl CoA/mg cytosolic protein respectively. In contrast, testicular FABP bound 254 and 139 pmol [14C]palmitoyl CoA/mg cytosolic protein in retinol sufficient and deficient groups. Retinol deficiency caused a tissue specific change in testicular FABP and not in liver FABP. Liver and testicular FABP's remained unchanged after four hour refeeding of retinol to retinol deficient rats.
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