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  • Title: Discovery of recurrent multiple brain states in non-convulsive status epilepticus.
    Author: van Putten MJ, van Putten MH.
    Journal: Clin Neurophysiol; 2007 Dec; 118(12):2798-804. PubMed ID: 17950030.
    Abstract:
    OBJECTIVE: We study burst-like patterns of epileptiform discharges in non-convulsive status epilepticus (SE). METHODS: Epileptiform burst-like transients were identified by estimating the amplitude envelope of the EEG signal, and recurrence and similarities were identified by pairwise matching in the time-domain. RESULTS: We identified similarities in the onset of a significant fraction of the epileptiform bursts, and a bimodal distribution of the burst durations. CONCLUSIONS: Bursts of epileptiform discharges during a non-convulsive SE are manifestations of multiple patterns of recurring brain states. SIGNIFICANCE: Quantitative description of ictal phenomena in epilepsy and status epilepticus adds to the knowledge of abnormal brain behavior and may assist in improved patient care.
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