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  • Title: High grade atrioventricular heart block in 2 adults with systemic lupus erythematosus.
    Author: Martinez-Costa X, Ordi J, Barberá J, Selva A, Bosch J, Vilardell M.
    Journal: J Rheumatol; 1991 Dec; 18(12):1926-8. PubMed ID: 1795334.
    Abstract:
    We describe 2 patients with systemic lupus erythematosus (SLE) and high grade atrioventricular (AV) block. In one patient anti-Ro antibodies were positive. This antibody has been associated with congenital complete heart block in children of mothers with SLE; however, its role in adult high grade AV block is not clear. We reviewed the 8 published cases of adults with SLE and high grade AV block. The possible mechanisms that could be implicated in the pathology of high grade AV block are discussed.
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