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  • Title: Integration of large-area polymer nanopillar arrays into microfluidic devices using in situ polymerization cast molding.
    Author: Chen G, McCandless GT, McCarley RL, Soper SA.
    Journal: Lab Chip; 2007 Nov; 7(11):1424-7. PubMed ID: 17960266.
    Abstract:
    Presented here is a simple and robust approach for the integration of mixed-scale (nm-cm) structures into fluidic devices. We report on devices composed of large-area polymer nanopillar arrays of high aspect ratio (33-667) integrated into microfluidic channels fabricated by cast-molding polymerization of methyl methacrylate with mechanically/lithographically patterned, nanoporous aluminium oxide (AAO) templates. The microchannels containing the nanopillar arrays can be chemically functionalized and used for a variety of applications, such as separation beds or solid-phase reactors/extractors.
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