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  • Title: [Tpeak-Tend interval and risk of cardiac events in patients with Brugada syndrome].
    Author: Wang JF, Shan QJ, Yang B, Chen ML, Zou JG, Chen C, Xu DJ, Cao KJ.
    Journal: Zhonghua Xin Xue Guan Bing Za Zhi; 2007 Jul; 35(7):629-32. PubMed ID: 17961428.
    Abstract:
    OBJECTIVE: To evaluate the possible association between Tpeak-Tend (Tp-e) interval in surface standard ECG and cardiac events in patients with Brugada syndrome (BrS). METHOD: Tp-e interval in surface standard ECG was compared between BrS patients (n = 23, all males) and paroxysmal supraventricular tachycardia (PSVT) patients (n = 20, all males) as well as between BrS patients with (n = 16) or without (n = 7) cardiac events. RESULTS: There was significant difference in Tp-e interval between BrS patients and PSVT patients [(109.57 +/- 22.86) ms vs. (88.50 +/- 13.08) ms, P < 0.05]. Tp-e interval was also significantly longer in BrS patients with cardiac events (syncope, clinical ventricular fibrillation and induced VF during electrophysiological study) than BrS patients without cardiac events [(118.12 +/- 20.40) ms vs. (90.00 +/- 15.27) ms, P < 0.05] while Tp-e interval was similar between BrS patients without cardiac events and PSVT patients (P > 0.05). CONCLUSION: The prolongation of Tp-e (> or = 120 ms) was associated with higher cardiac events in BrS patients.
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