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  • Title: [Vitamin D insufficiency--possible etiologic factor of autoimmune diseases].
    Author: Jørgensen SP, Bartels LE, Agnholt J, Glerup H, Nielsen SL, Hvas CL, Dahlerup JF.
    Journal: Ugeskr Laeger; 2007 Oct 22; 169(43):3655-60. PubMed ID: 17967265.
    Abstract:
    The primary source of vitamin D in humans is sun exposure to the skin. The incidence of certain autoimmune diseases correlates positively with latitude. As vitamin D production increases with sun exposure, vitamin D insufficiency is hypothesised to influence the development of autoimmune diseases. In experimental animal and cellular studies in vitro 1.25-(OH)2-vitamin D reduces inflammation. This article discusses the role of vitamin D in inflammatory bowel disease, type 1 diabetes mellitus, multiple sclerosis, and rheumatoid arthritis.
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