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  • Title: Considerations for generic oncology FDG-PET/CT protocol preparation in drug development.
    Author: Hallett WA, Maguire RP, McCarthy TJ, Schmidt ME, Young H.
    Journal: IDrugs; 2007 Nov; 10(11):791-6. PubMed ID: 17968761.
    Abstract:
    [18F]Fluorodeoxyglucose (FDG)-PET combined with CT is increasingly being used as an imaging tool in oncology clinical trials. Progress in the standardization and harmonization of acquisition and analysis protocols for FDG-PET/CT has been made, although there are still areas for which further guidance is needed. Standardizing FDG-PET/CT clinical trial design and interpretation will contribute to increased efficiency and precision in decision-making for drug development. This feature review highlights areas in FDG-PET/CT imaging, particularly image analysis and response classification, that currently require expert guidance or further research to optimize the application of this tool in oncological drug development.
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