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  • Title: [The influence of dysgenic sterility on sexual dimorphism of life span in Drosophila Melanogaster].
    Author: Shaposhnikov MV, Moskalev AA.
    Journal: Adv Gerontol; 2007; 20(1):40-6. PubMed ID: 17969584.
    Abstract:
    It was analyzed the life span of fertile and sterile (as a result of P-M hybrid dysgenesis) flies. In investigation the F1 hybrids from the crosses of wild type Drosophila strains Canton-S (M) and Harwich (P) were used. Reciprocal crosses of these strains enable to obtain fertile and sterile hybrids with the same genotypes. It is shown the reduction of life span in sterile females and an increase of life span in sterile males. The obtained results indicate that signals from male and female gonads have opposite effects on longevity. Whereas in fertile flies sexual dimorphism that manifested in greater female longevity was observed, in sterile flies females had duration of life close to males. The leveling of the life span characteristics in sterile females and males shows that mechanism of sexual life span differences relates to reproductive system. It seems to be possible that testicles induce some mechanism that shortens males life span, and ovaries are the source of the signal extending females life span.
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