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  • Title: [Turner's syndrome with mosaic karyotype and renovascular hypertension].
    Author: Jelić S, Marisavljević D.
    Journal: Srp Arh Celok Lek; 1997; 125(1-2):48-50. PubMed ID: 17974355.
    Abstract:
    An 18-year-old patient with Turner's syndrome with mosaic karyotype (45,XO/46, Xi(Xq)) and renovascualr hypertension is presented. The problem of cytogenetic diagnosis of mosaic Turner's syndrome and the problem of aetiology of hypertension in these patient is discussed. Arterial hypertension, manifested at the age of 19 years, and considered as a side-effect of aestrogen replacement therapy, was the reason of its discontituation. Regular diagnostic procedures confirmed the renovascular aetiology of the existing hypertension, and percutaneous transluminal angioplasty of the narrow segment of the right upper renal artery made the necessary replacement therapy possible. In classic medical manuals hypertension in Turner's syndrome was usually mentioned as "unexplained". During the last 10 years only one attempt in elucidation of pathogenesis of arterial hypertension in Turner's syndrome was reported as well as only one case of renovascular hypertension in a patient with Turner's syndrome.
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