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  • Title: Daily variation in concentration of plasma corticosteroid in hypophysectomized rats.
    Author: Meier AH.
    Journal: Endocrinology; 1976 Jun; 98(6):1475-9. PubMed ID: 179796.
    Abstract:
    A daily variation in the concentration of plasma corticosteroid hormone is present in hypophysectomized rats implanted with pellets of adrenocorticotropic hormone (ACTH) and thyroxine. Although ACTH is necessary to maintain a functional adrenal, and thyroxine is required to permit the expression of the plasma corticosteroid rhythm, a normal daily variation in plasma corticosteroid concentration does not appear to depend on the periodic release of pituitary hormones.
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