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Title: Use of the QuantiFERON-TB Gold test in Japanese patients with sarcoidosis. Author: Inui N, Suda T, Chida K. Journal: Respir Med; 2008 Feb; 102(2):313-5. PubMed ID: 17980570. Abstract: BACKGROUND AND OBJECTIVE: Mycobacterium tuberculosis has been proposed as a candidate agent for the cause of sarcoidosis. The QuantiFERON-TB Gold test has a higher specificity for detecting M. tuberculosis infection than the conventional tuberculin skin test. This study aimed to investigate the rate of positive QuantiFERON-TB Gold results in Japanese sarcoidosis patients. PATIENTS AND METHODS: The QuantiFERON-TB Gold test, an enzyme-linked immunosorbent assay, was used to assess the levels of interferon-gamma resulting from immune responses to M. tuberculosis-specific antigens, namely early secretory antigen target 6 and culture filtrate protein 10, in 90 Japanese sarcoidosis patients. RESULTS: The QuantiFERON-TB Gold result was positive in 3 of the 90 patients tested. CONCLUSION: The positivity rate of QuantiFERON-TB Gold was 3.3% in Japanese sarcoidosis patients.[Abstract] [Full Text] [Related] [New Search]