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Title: Systemic mastocytosis with diffuse cutaneous involvement and haematological disease presenting in utero treated unsuccessfully with vincristine. Author: Angus J, Leach IH, Grant J, Ravenscroft JC. Journal: Clin Exp Dermatol; 2008 Jan; 33(1):36-9. PubMed ID: 17983456. Abstract: Mastocytosis is a disorder characterised by abnormal mast cell proliferation. The diverse spectrum of clinical presentations is dependent on the tissues and organs involved. We report a rare case of aggressive systemic mastocytosis presenting in utero with diffuse cutaneous involvement, and haematological abnormalities. There is little published evidence to guide treatment.[Abstract] [Full Text] [Related] [New Search]