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  • Title: [Changes in the functional state and structure of the adrenals in CC14 poisoning].
    Author: Iakobson GS, Gizatulin ZIa, Shorin IuP, Subbotin VM.
    Journal: Farmakol Toksikol; 1975; 38(3):349-52. PubMed ID: 179852.
    Abstract:
    Introduction of CCI4 in doses of 0.1 and 0.2 ml/100 g to albino rats reduced the steroid production generated by adrenal sections. In 24 and 48 hours after poisoning with a small dose of CCI4 (0.1 ml/100 g) there could be seen an increased concentration of 11-oxycorticosteroids in the plasma. Morphological signs of a damage suffered by the gland were observed only in poisoning with a large dose of CCI4 (0.2 ml/100 g).
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