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  • Title: Multicomponent reactions in solid-phase synthesis.
    Author: Banfi L, Guanti G, Riva R, Basso A.
    Journal: Curr Opin Drug Discov Devel; 2007 Nov; 10(6):704-14. PubMed ID: 17987522.
    Abstract:
    Multicomponent reactions are a powerful tool in combinatorial chemistry and diversity-oriented synthesis for the assembly of collections of complex molecules in a highly straightforward and efficient manner. Additional advantages in terms of isolation and purification can be obtained by performing these condensations on a polymeric support or with the aid of solid-supported reagents, scavengers or catalysts. This review covers research published in this area during the last two years and provides a perspective of future directions.
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