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  • Title: Synthesis of dendrimers and drug-dendrimer conjugates for drug delivery.
    Author: Najlah M, D'Emanuele A.
    Journal: Curr Opin Drug Discov Devel; 2007 Nov; 10(6):756-67. PubMed ID: 17987527.
    Abstract:
    Dendrimers constitute a class of polymers that possess a well-defined structure allowing the precise control of size, shape and terminal group functionality. Their utility has been explored for a wide range of pharmaceutical applications. There is growing interest in the design and synthesis of novel biocompatible dendrimers and a number of novel dendrimer architectures are discussed in this review. Recently, there has also been interest in the design of drug-dendrimer prodrugs and several of these systems are described, with emphasis on how the properties of such carriers may be tailored via surface engineering.
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