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  • Title: Synthesis, antitubercular and anticancer activities of substituted furyl-quinazolin-3(4H)-ones.
    Author: Raghavendra NM, Thampi P, Gurubasavarajaswamy PM, Sriram D.
    Journal: Arch Pharm (Weinheim); 2007 Dec; 340(12):635-41. PubMed ID: 17994604.
    Abstract:
    Some novel substituted-3-{[(1E)-(substituted-2-furyl)-methylene]amino}quinazolin-4(3H)-one (5, 6, 7) a-f were synthesized by a multi-step process. These synthesized compounds are characterized by various spectroscopic techniques and evaluated for their antitubercular and anticancer activities. Biological activity indicated that some of the title compounds are potent antitubercular and anticancer agents.
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