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  • Title: Can we smell without an olfactory bulb?
    Author: Rombaux P, Mouraux A, Bertrand B, Duprez T, Hummel T.
    Journal: Am J Rhinol; 2007; 21(5):548-50. PubMed ID: 17999787.
    Abstract:
    BACKGROUND: Lack of an olfactory bulb (OB) is typically associated with anosmia. METHODS: We present a patient with subnormal olfactory function in whom the OB could not be detected with magnetic resonance imaging (MRI). RESULTS: Olfactory function was evaluated on two occasions. Orthonasal olfactory function was assessed with the "Sniffin' Sticks" test providing a score equivalent to hyposmia. Retronasal olfactory function was studied with "smell powders" indicating a decreased, but not absence of, olfactory function. Importantly, chemosensory event-related potentials were clearly present in response to olfactory and trigeminal stimuli. CONCLUSION: This indicates that olfactory function may be present in some subjects even when an OB can not be detected with MRI.
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