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  • Title: Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode.
    Author: Angell RM, Bamborough P, Cleasby A, Cockerill SG, Jones KL, Mooney CJ, Somers DO, Walker AL.
    Journal: Bioorg Med Chem Lett; 2008 Jan 01; 18(1):318-23. PubMed ID: 18006306.
    Abstract:
    The biphenyl amides (BPAs) are a novel series of p38 MAP kinase inhibitors. The discovery of the series through structure-based focused screening is described, and the binding mode of the compounds is explained with reference to X-ray crystal structures.
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