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  • Title: Pyrazolo[4,3-e][1,2,4]triazines: purine analogues with electronic absorption in the visible region.
    Author: Mojzych M, Rykowski A, Wierzchowski J.
    Journal: Molecules; 2005 Oct 31; 10(10):1298-306. PubMed ID: 18007523.
    Abstract:
    Synthesis of several pryrazolo[4,3-e][1,2,4]-triazines is described. The absorption spectrum of some 5-substituted derivatives was found to extend to the visible region. These compounds were found to inhibit some enzymes of purine metabolism, like xanthine oxidase or bacterial purine-nucleoside phosphorylase with Ki values in the 10(-3) -10(-5) M range.
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