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  • Title: Role of Thy-1,2+ cells in the regulation of hemopoiesis during severe hypoxia.
    Author: Goldberg ED, Dygai AM, Zyuz'kov GN.
    Journal: Bull Exp Biol Med; 2007 Jan; 143(1):18-21. PubMed ID: 18019003.
    Abstract:
    We studied the state of the bone marrow Thy-1,2+ cell pool under conditions of severe hypoxia. T cell mechanisms of hemopoiesis regulation are preserved under conditions of severe oxygen deficiency due to changes in functional properties of Thy-1,2+ cells. We revealed an indirect (mediated through cooperation with adherent myelokaryocytes) stimulating effect of Thy-1,2+ cells on erythroid precursors as well as direct and indirect feeder effects of these cells on granulocyte-monocyte precursors.
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