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  • Title: Antioxidant phenylpropanoid-substituted epicatechins from Trichilia catigua.
    Author: Tang W, Hioki H, Harada K, Kubo M, Fukuyama Y.
    Journal: J Nat Prod; 2007 Dec; 70(12):2010-3. PubMed ID: 18020420.
    Abstract:
    Two new phenylpropanoid-substituted epicatechins, namely, catiguanin A ( 1) and catiguanin B ( 2), were isolated from the bark of Trichilia catigua along with four known compounds, cinchonain Ia ( 3), cinchonain Ib ( 4), cinchonain Ic ( 5), and cinchonain Id ( 6). The structures of 1 and 2 were elucidated by analysis of spectroscopic data and by comparison of their NMR data with those of previously reported cinchonains. The isolated compounds exhibited potent antioxidant activity in the alpha,alpha-diphenyl-beta-picrylhydrazyl (DPPH) radical scavenging test, with IC 50 values in the 2.3-9.4 microM range.
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