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  • Title: Albright's hereditary osteodystrophy with extensive heterotopic ossification of the oral and maxillofacial region: how fetuin research may help a seemingly impossible condition.
    Author: DuVal MG, Davidson S, Ho A, Cohen R, Park M, Nourian S, Baker G, Sándor GK.
    Journal: J Can Dent Assoc; 2007 Nov; 73(9):845-50. PubMed ID: 18028761.
    Abstract:
    Albright"s hereditary osteodystrophy (AHO) is a complex genetic disorder characterized by brachydactyly, gonadotropin resistance, hypothyroidism, pseudohypoparathyroid syndrome and heterotopic ossification. Heterotopic ossification rarely occurs in the maxillofacial region. In this article, we present such a case, describe the etiology, characteristics and treatment of AHO and suggest a potential role of an inhibitor of bone formation such as fetuin in preventing recurrence of aberrant ossification.
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