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  • Title: [Diagnostic potential of the lower-body negative pressure test in medical monitoring during extended space flights].
    Author: Aslferova IV, Turchaninova VF, Golubchikova ZA, Krivolapov VV, Khorosheva EG.
    Journal: Aviakosm Ekolog Med; 2007; 41(4):25-9. PubMed ID: 18035710.
    Abstract:
    To put into service the diagnostic and prognostic capabilities of the lower body negative pressure test (LBNP) during extended space flights, cardiovascular reactions associated with various levels of test tolerance were analyzed and compared. The article gives account of 60 tests performed by 44 cosmonauts 33 to 53 years of age during 59- to 415-d flights. In 36 tests tolerance was good and in 24 - satisfactory. Medical evaluation was fulfilled using GaMMa-1M, an onboard multifunctional medical monitoring system. Dynamics of ECG, blood pressure, stroke and minute volumes, pulse filling, and vertebral-basilar tone exhibited some specific traits that mirrored LBNP tolerance. Established were diagnostically implicative values in the course of pressure drop. Evidence was obtained that during the test and ensuing data analysis consideration should be given as to the span of changes of each parameter, so the time of their initiation, and dynamics.
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