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  • Title: Treatment of chronic portosystemic encephalopathy in cirrhotic patients by embolization of portosystemic shunts.
    Author: Zidi SH, Zanditenas D, Gelu-Siméon M, Rangheard AS, Valla DC, Vilgrain V, Pelletier GM.
    Journal: Liver Int; 2007 Dec; 27(10):1389-93. PubMed ID: 18036102.
    Abstract:
    UNLABELLED: AIMS/BACKGROUNDS: Large spontaneous portal-systemic shunts can occasionally be the cause of chronic and disabling encephalopathy in cirrhotic patients. Shunt embolization has been proposed, however the clinical relevance of this technique remains uncertain. METHODS/RESULTS: We report our results in seven patients treated by shunt embolization. Although the procedure was achieved and technically successful in all patients, the clinical results were poor as long-term improvement was obtained in only one patient. Three patients died within 3 months after the procedure from cirrhoses' end stage complications. CONCLUSION: We believe that optimal management of these patients with chronic spontaneous encephalopathy is liver transplantation.
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