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  • Title: Primary malignant fibrous histiocytoma of the heart with skeletal muscles metastases.
    Author: Milicic D, Juretic A, Bulum J, Saric N, Bisof V, Jelic I, Jelasic D.
    Journal: J Card Surg; 2007; 22(6):513-6. PubMed ID: 18039217.
    Abstract:
    Malignant fibrous histiocytoma is an extremely rare primary malignant tumor of the heart. It is usually diagnosed when it is locally aggressive or has already metastasized. The prognosis is poor with an average survival time of one year. We report a case of recurrent left atrial malignant fibrous histiocytoma initially misdiagnosed as myxoma. The patient underwent repeated surgical resections followed by chemotherapy. Despite adjuvant chemotherapy, 18 months after initial diagnosis, definitive tumor relapse in left atrium was diagnosed. This is the 48th case of primary cardiac fibrous malignant histiocytoma reported in the literature.
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