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  • Title: Route of administration for erythropoiesis-stimulating agents: patient and nursing considerations.
    Author: Holloway M.
    Journal: Nephrol Nurs J; 2007; 34(5):527-31. PubMed ID: 18041455.
    Abstract:
    Several clinical studies have indicated that compared with intravenous (IV) administration, subcutaneous (SC) administration of Epoetin alfa may result in a dose-sparing effect in patients on hemodialysis. However, data also indicate wide inter-patient variability in response, with many patients requiring the same or a higher dose following conversion to SC administration. Convenience favors IV administration of Epoetin alfa in patients on hemodialysis, and patient preferences and comfort should also be primary considerations. For patients who prefer SC injections, the nurse's coordination of the required dosing, administration, and operational factors is key to maintaining and improving anemia-related outcomes.
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