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  • Title: tRNA traffic meets a cell-cycle checkpoint.
    Author: Weinert T, Hopper AK.
    Journal: Cell; 2007 Nov 30; 131(5):838-40. PubMed ID: 18045528.
    Abstract:
    The molecular pathways linking DNA-damage checkpoint proteins to cell-cycle progression remain largely unresolved. Findings by Ghavidel et al. (2007) reported in this issue suggest that tRNA trafficking and the transcription factor Gcn4 are key intermediates in the process by which yeast cells detect DNA damage and delay cell-cycle progression at the G1 to S phase transition.
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