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  • Title: Effect of culture conditions on canthaxanthin production by Dietzia natronolimnaea HS-1.
    Author: Khodaiyan F, Razavi SH, Emam-Djomeh Z, Mousavi SM, Hejazi MA.
    Journal: J Microbiol Biotechnol; 2007 Feb; 17(2):195-201. PubMed ID: 18051749.
    Abstract:
    This study investigated the effects of various culture parameters (carbon sources, temperature, initial pH of culture, NaCl concentration, and light) on the growth and canthaxanthin production by Dietzia natronolimnaea HS-1. The results showed that the most effective carbon source for growth and canthaxantin production was glucose, and the best pH and temperature were 7 and 31 degrees C, respectively. In addition, the biomass and canthaxanthin production increased in a medium without NaCl and in the presence of light. Under the optimized conditions, the maximum biomass, total carotenoid, and canthaxanthin production were 6.12 +/- 0.21 g/l, 4.51 +/- 0.20 mg/l, and 4.28 +/- 0.15 mg/l, respectively, in an Erlenmeyer flask system, yet increased to 7.25 g/l, 5.48 mg/l, and 5.29 mg/l, respectively, in a batch fermenter system.
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