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  • Title: [Regenerative response of hepatocytes implanted in the spleen].
    Author: García-Alonso I, Barceló P, Portugal V, Bilbao J, de Tejada IL, Méndez J.
    Journal: Rev Esp Enferm Dig; 1991 Oct; 80(4):247-51. PubMed ID: 1805890.
    Abstract:
    Regenerative activity of syngenic hepatocytes inoculated into the spleen has been assessed. Partial hepatectomy and cyclosporine were used as regenerative stimuli. Nuclear DNA has been quantified by means of a cytophotometric method, and the intensity of the response has been defined as the Mean Percentage of Regenerating Hepatocytes (MPRH). Both hepatectomy and cyclosporine (alone or associated) have significantly increased splenic MPRH.
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