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  • Title: World disparities in risk definition and management of retinoblastoma: a report from the International Retinoblastoma Staging Working Group.
    Author: Chantada GL, Doz F, Orjuela M, Qaddoumi I, Sitorus RS, Kepak T, Furmanchuk A, Castellanos M, Sharma T, Chevez-Barrios P, Rodriguez-Galindo C, International Retinoblastoma Staging Working Group.
    Journal: Pediatr Blood Cancer; 2008 Mar; 50(3):692-4. PubMed ID: 18059037.
    Abstract:
    Following from the publication of the International Retinoblastoma Staging System, an open internet discussion group was created at the www.cure4kids.org resource. The results of a survey distributed among participants are discussed. Although most patients with retinoblastoma were treated under prospective protocols, there was a wide variation in the definition of risk criteria and in the criteria for giving adjuvant chemotherapy following enucleation. Definition of high-risk histological features and the criteria for use of adjuvant therapy will be standardized in future studies. Internet meetings are a valuable mechanism for enabling participation from under-resourced countries in the development of cooperative studies.
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