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  • Title: Prophylactic human papillomavirus vaccination: a breakthrough in primary cervical cancer prevention.
    Author: Garcia FA, Saslow D.
    Journal: Obstet Gynecol Clin North Am; 2007 Dec; 34(4):761-81, ix. PubMed ID: 18061868.
    Abstract:
    Nearly all cervical cancers require human papillomavirus infection (HPV) for subsequent carcinogenesis. The identification of this obligate viral etiology, in addition to a vast knowledge about the HPV viral life cycle and resultant host response, has led to a vaccine approach to cervical cancer prevention. The use of prophylactic cancer vaccine as primary prevention holds the most promise for long-term cancer prevention but raises some important and as yet unanswered questions that are addressed in this article.
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