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  • Title: Formation of substituted pyrroles via an imine condensation/Aza-Claisen rearrangement/imine-allene cyclization process by MAOS.
    Author: Bremner WS, Organ MG.
    Journal: J Comb Chem; 2008; 10(1):142-7. PubMed ID: 18062673.
    Abstract:
    A diverse collection of pyrroles has been prepared using a one-pot, domino aldehyde/amine condensation, [3,3]-aza-Claisen rearrangement, imine-allene cyclization strategy. This protocol was accelerated by microwave irradiation and provided very good levels of conversion after reacting for only 30 min.
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