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  • Title: Skin metastases revealing a bilateral ovarian invasive micropapillary serous carcinoma.
    Author: Moussa A, Denguezli W, Njim L, Haddad A, Faleh R, Sakouhi M, Zakhama A.
    Journal: Arch Gynecol Obstet; 2008 Jul; 278(1):71-4. PubMed ID: 18066568.
    Abstract:
    Skin involvement is a late complication that rarely occurs in ovarian cancer patients. This event invariably carries a bad prognosis in the course of an advanced stage ovarian carcinoma which is usually of the conventional serous type. Micropapillary serous carcinoma (MPSC) was recently recognized as a distinct neoplasm that seems to be less aggressive than conventional serous ovarian carcinoma. Indeed, a few cases of stage IV MPSC have been reported. Herein, we describe an unusual case of ovarian invasive MPSC occurring in a young woman, particularly by its mode of presentation as multiple subcutaneous nodules that were subsequently diagnosed as metastatic lesions. This case demonstrates the potential of MPSC for aggressive clinical behaviour.
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