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  • Title: New developments of the "lock-in" modified cycloSal-d4TMPs.
    Author: Vukadinović-Tenter D, Balzarini J, Meier C.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2007; 26(10-12):1325-8. PubMed ID: 18066777.
    Abstract:
    New developments of the "lock-in" modified cycloSal-d4TMP are reported. Novel prodrugs with variations in the linker chain were introduced. The synthesis, hydrolysis properties in different media (PBS, CEM/0- and liver extracts) and the antiviral activities against HIV are shown.
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