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  • Title: Stabilization of multi-stranded nucleic acid structures using 3'-S-phosphorothiolate linkages.
    Author: Cosstick R, Buckingham J, Brazier J, Fisher J.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2007; 26(6-7):555-8. PubMed ID: 18066854.
    Abstract:
    3 '-S-Phosphorothiolate linkages incorporated into an oligodeoxynucleotide have been shown to stabilise duplex formation with a complementary RNA strand, but destabilise a duplex formed with a complementary DNA strand. The four-stranded i-motif structure is also stabilised this modification.
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