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  • Title: A total synthesis of OSW-1.
    Author: Xue J, Liu P, Pan Y, Guo Z.
    Journal: J Org Chem; 2008 Jan 04; 73(1):157-61. PubMed ID: 18067313.
    Abstract:
    A new and practical method was developed to synthesize OSW-1, a natural saponin with potent antitumor activities, from (+)-dehydroisoandrosterone, l-arabinose, and D-xylose on gram scale. The synthesis was achieved in 10 linear steps with an overall yield of 6.4% starting from (+)-dehydroisoandrosterone.
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