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  • Title: [Prevalence and predictors of microalbuminuria in persons with various glucose tolerance levels].
    Author: Huo L, Xu M, Huang HE, Li R, Dai M, Wang JG, Ning G, Li XY.
    Journal: Zhonghua Yi Xue Za Zhi; 2007 Sep 25; 87(36):2537-40. PubMed ID: 18067826.
    Abstract:
    OBJECTIVE: To investigate the prevalence of microalbuminuria in persons with various glucose tolerance levels and the risk factors for the development of microalbuminuria. METHODS: Early morning urine samples were collected from 1,779 subjects with all the data necessary for this survey from a population screened in Baoshan Community, Shanghai by cluster sampling, including 752 with normal glucose tolerance (NGT), 505 impaired glucose tolerance (IGR), and 522 type 2 diabetes mellitus (T2DM) diagnosed according to a 75 g oral glucose tolerance test (OGTT). Urinary albumin-to-creatinine ratio (ACR) was measured by rate-nephelometry method. RESULTS: (1) The incidence rate of MAU of the T2DM group was 11.3%, significantly higher than those of the NGT and IGR groups (4.7% and 6.1% respectively, both P < 0.01). (2) Logistic regression showed that MAU was significantly correlated with 2 h PG, systolic blood pressure, and triglyceride. CONCLUSION: The prevalence of MAU is significantly higher in the diabetic patients. 2 h PG, systolic blood pressure, and triglyceride and independent risk factors of MAU.
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