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  • Title: Microwave-assisted synthesis and antimicrobial activities of flavonoid derivatives.
    Author: Abdel Ghani SB, Weaver L, Zidan ZH, Ali HM, Keevil CW, Brown RC.
    Journal: Bioorg Med Chem Lett; 2008 Jan 15; 18(2):518-22. PubMed ID: 18068365.
    Abstract:
    Eleven flavonoid derivatives were synthesised using a modified Baker-Venkataraman rearrangement, and subsequent microwave-assisted closure of the heterocyclic ring. All of the synthetic compounds displayed antifungal activity against Aspergillus niger and Fusarium oxysporium, and two of the synthetic flavonoid analogues exhibited significant activity against methicillin-resistant Staphylococcus aureus.
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