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  • Title: [Comparison of peripapillary atrophy in eyes with unilateral visual field defect in patients with primary open-angle glaucoma and normal tension glaucoma].
    Author: Pan YZ, Ren ZQ, Li M, Qiao RH.
    Journal: Zhonghua Yan Ke Za Zhi; 2007 Sep; 43(9):784-7. PubMed ID: 18070521.
    Abstract:
    OBJECTIVE: To evaluate the difference of the peripapillary atrophy between two eyes of unilateral visual field defect in each of patient with primary open-angle glaucoma (POAG) and normal tension glaucoma (NTG). METHODS: This study included 40 eyes with unilateral visual field defect in patients with POAG (20 cases) and NTG (20 cases). Color stereo optic disc photographs were morphometrically evaluated by a video camera and a computer system. The refractive range (spherical equivalent) of all these subjects was between -3.00D and +3.00D. RESULTS: The cup areas (CA) and cup/disc areas (CA/DA) in eyes with visual field defect were significantly larger than in eyes with normal visual field (CA: t=5.332, P<0.01; CA/DA: t=5.126, P<0.01). The alpha zone areas (alphaA) of PPA were significantly enlarged in visual field defect eyes compared with visual field normal eyes (t=3.02, P=0.0045), while there is no significant difference in beta-zone area (betaA) between two eyes. (S=13.5, P=0.426). The frequency of the PPA (alpha-zone and beta-zone) occurrence were also similar in both eyes. (alphaA: chi(2)=0.00, P=1.000; betaA: chi(2)=1.2857, P=0.2568). CONCLUSION: The results suggest that either beta-zone area or the presence of PPA is not closely correlated to the visual field defect in POAG and NTG patients with exclusion of moderate or high myopia.
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