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  • Title: [The role of the complement system in the origin of respiratory insufficiency in patients on hemodialysis].
    Author: Neĭmark MI.
    Journal: Klin Med (Mosk); 1991 Nov; 69(11):79-81. PubMed ID: 1808418.
    Abstract:
    A study was made of changes in functional status of complementary system in 42 patients with chronic renal failure on programmed hemodialysis. Early stages of hemodialysis were accompanied by short-term and reversible activation of complementary system. 100 sessions were followed by complement depression. Complement system was found to be involved in two pathogenetic mechanisms of respiratory insufficiency: block of pulmonary microcirculation by leukocytic aggregates and DIC syndrome associated with microthrombosis of the lesser circulation vessels. To manage the above complications, plasmapheresis is advocated.
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