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  • Title: How do geometric factors influence epidural spinal cord stimulation? A quantitative analysis by computer modeling.
    Author: Holsheimer J, Struijk JJ.
    Journal: Stereotact Funct Neurosurg; 1991; 56(4):234-49. PubMed ID: 1808648.
    Abstract:
    Effects of both anatomic and electrode geometry on the recruitment of rostrocaudal fibers in the spinal cord were investigated by computer simulation of epidural spinal cord stimulation. A three-dimensional model was used, representing the geometry and electrical conductivity of the spinal cord and surrounding tissues, in combination with a model representing the electrical properties of a myelinated nerve fiber. Recruitment contours in the dorsal columns were calculated at various spinal geometries as a function of electrode position, combination and area. Cathodal position appeared to be most significant. Recruitment areas resulting from different contact combinations of a mediodorsal array were almost identical. It was shown that perception threshold largely depends on both dorsal cerebrospinal fluid width and fiber size. The usual bipolar contact separation appeared to approximate the theoretically optimal value, resulting in maximum fiber recruitment at minimum stimulus.
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