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  • Title: Combined hepatocellular carcinoma and cholangiocarcinoma: a case report and review of the literature.
    Author: Zhou YM, Yang JM, Wang B, Xu F, Tong Y, Li DQ.
    Journal: Hepatobiliary Pancreat Dis Int; 2007 Dec; 6(6):656-9. PubMed ID: 18086637.
    Abstract:
    BACKGROUND: Combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) is a rare histopathologic form of primary liver cancer. We report a case of cHCC-CC and review the literature. METHOD: The clinicopathological features of a 61-year-old male were retrospectively analyzed. RESULTS: Hepatocellular carcinoma (HCC) was preoperatively considered on the basis of clinical findings resembling those associated with HCC. Hepatectomy was therefore performed. Microscopically, the specimen displayed histological features of cHCC-CC. The patient has remained alive after follow-up for 3 months without evidence of recurrence and metastasis. CONCLUSION: It is difficult to make a correct preoperative diagnosis of cHCC-CC and hepatic resection is the treatment of choice.
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