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  • Title: [The role of temperature as a factor of structure and functional fit of a "prey" virus based on the example of phage T4].
    Author: Khusainov AA, Shil'nikov GV, Emel'ianenko VI, Ivanitskiĭ GR.
    Journal: Biofizika; 1991; 36(6):973-81. PubMed ID: 1809394.
    Abstract:
    By means of high-precision acoustic measurements and by the methods of fluorescent and electron microscopy investigations were performed of thermoinduced conformational changes in T4 bacteriophage and its thermolabile mutants altered in baseplate proteins (gene products "7", "8", "10"). A relationship was found between the conformational changes in T4 bacteriophage structure in the temperature range of 33-45 degrees C and the efficiency of bacteriophage adsorption and changes in the orientation of long tail fibers. Possibility of heat regulation of "recognition" of "host" cells by bacterial viruses is suggested.
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