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  • Title: A multicomponent synthesis of triazinane diones.
    Author: Groenendaal B, Vugts DJ, Schmitz RF, de Kanter FJ, Ruijter E, Groen MB, Orru RV.
    Journal: J Org Chem; 2008 Jan 18; 73(2):719-22. PubMed ID: 18095703.
    Abstract:
    An efficient, one-pot synthetic protocol toward triazinane diones, a rather unexplored class of heterocyclic scaffolds combining phosphonates, nitriles, aldehydes, and isocyanates is described. The optimization of the reaction, synthesis of a small library of different triazinane diones, as well as alternative routes toward the triazinane dione scaffold are discussed.
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