These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Loudness dependence of the auditory evoked N1/P2 component as an indicator of serotonergic dysfunction in patients with schizophrenia--a replication study.
    Author: Juckel G, Gudlowski Y, Müller D, Ozgürdal S, Brüne M, Gallinat J, Frodl T, Witthaus H, Uhl I, Wutzler A, Pogarell O, Mulert C, Hegerl U, Meisenzahl EM.
    Journal: Psychiatry Res; 2008 Feb 28; 158(1):79-82. PubMed ID: 18096246.
    Abstract:
    Serotonergic dysfunction appears to be involved in the pathogenesis of schizophrenia. The loudness dependence of auditory evoked potentials (LDAEP) has been suggested to be a valid indicator of the brain serotonin system's activity in humans. Patients with schizophrenia showed weaker LDAEP, indicating high serotonergic activity, in comparison to healthy controls. Thus, we were able again to demonstrate electrophysiological evidence for an upregulated serotonergic system in schizophrenia.
    [Abstract] [Full Text] [Related] [New Search]