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  • Title: Tc-99m HMPAO labeled white blood cell imaging in a child with eosinophilic lung disease.
    Author: Moralidis E, Papakonstantinou E, Arsos G, Boussios N, Koliouskas D, Karakatsanis C.
    Journal: Clin Nucl Med; 2008 Jan; 33(1):38-40. PubMed ID: 18097257.
    Abstract:
    In radiolabeled leukocyte imaging, Tc-99m HMPAO has a significantly higher selectivity for eosinophils than neutrophils, but this may be clinically meaningful in disorders with eosinophilic infiltration. We present the case of a 2-year-old boy with infection who also developed drug-induced eosinophilic lung disease, as established later by bronchoalveolar lavage and discontinuation of the responsible antistaphylococcal agent. In the investigation of sepsis, diffusely increased pulmonary accumulation of Tc-99m HMPAO labeled leukocytes was observed. These findings were consistent with eosinophilic lung infiltration and underline the importance of clinical and laboratory data in the comprehensive interpretation of Tc-99m HMPAO labeled leukocytes scans.
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